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How Sildenafil (Viagra) works. Sildenafil (Viagra) is a phosphodiesterase-5 (PDE-5) inhibitor. PDE-5 is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks PDE-5, sildenafil (Viagra) helps an erection occur by allowing certain muscles in the penis to relax and the penis to fill with blood. Considering taking the little blue pill for the first time? We got you covered: all you need to know on what to expect when using Viagra for the first time. The main obstacle in my practice is the cost, Dr. Liou says. You’ll need to work with your doctor to get the pill you need at a price you can afford. What erectile dysfunction pills are available? In addition to Viagra, other ED drugs available in the United States include avanafil (Stendra), tadalafil (Cialis) and vardenafil (Levitra). does viagra works Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is also sometimes used off Overall, Viagra begins to work within 1 hour for most men. However, if you ve tried taking Viagra multiple times and it doesn t seem to work at all, talk to your healthcare professional (HCP). They may recommend an alternative ED medication. Important: Viagra only works when you re aroused. If you re not aroused, Viagra likely won t

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